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Radical
/ˈrædɪkəl/
Relating to or affecting fundamental aspects of something, generally involving significant change or differences from the norm.
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Examples:
Grent Blackfur is a known terrorist and radical.
Hence is the need for radical change in schools.
The doctor suggested a radical treatment to cure the disease.
Etymology:
From Late Latin radicalis meaning of or pertaining to the root, derived from Latin radix meaning root. It entered Middle English in the late 14th century.