Her approach to problem-solving greatly differs from his.The architecture differs from region to region significantly.This year's design differs from previous versions.
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Differ with
/ˈdɪfər wɪð/
To have a different opinion or to not agree with someone or something
Examples:
She tends to differ with her colleagues on policy matters.The artist's vision may differ with the curator's idea.His experience made him differ with the general consensus.
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Ways to tell them apart:
Remember that differ from is about highlighting distinctions between objects or concepts.
Use differ with when you want to express disagreement with someone else's opinion.
Think from as separating things, while with involves interaction between people.
Consider differ from as a comparison phrase and differ with as a conflict resolution.
In a debate, you may differ with a person but differ from a previous argument.